Fight on Isla de Muerta 17
"It's not a bad look, really. Eh?"
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"The ship can't survive this pounding for long!"
―Anonymous pirate on the Black Pearl[src]

The Sea of Despair was a sea located in an unknown part of the world.

Captain Jack Sparrow, guided by John Stryke, took the Black Pearl into the Sea of Despair, intent on finding the large ruby treasure of the Grotto of Despair.

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