The Keys were originally inhabited by Calusa and Tequesta natives. They were later found and charted by Juan Ponce de León in 1513. Ponce de León named the islands Los Martires ('The Martyrs') as they looked like suffering men from a distance. "Key" is corrupted from the Spanish Cayo, meaning small island. For many years, Key West was the largest town near Florida, and it grew prosperous on wrecking. The isolated outpost was well located for trade with Cuba, the Bahamas, and was on the main trade route from New Orleans.
- The Price of Freedom (First mentioned)
- Pirates of the Caribbean: At World's End (On a map)
- Pirates of the Caribbean: On Stranger Tides (On a map)